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AOD-9604 is a synthetic 16-amino-acid peptide corresponding to the C-terminal lipolytic fragment of human growth hormone (residues 177191), with an N-terminal tyrosine added for stability

Accordingly, in the CY 2025 OPPS/ASC final rule with comment period, we finalized a policy to exclude the non-opioid treatments for pain relief identified as satisfying the required criteria for payment under section 4135 of the CAA, 2023 from the C-APC policy to ensure payment is not packaged into any C-APC and that separate payment is made in accordance with the statute (89 FR 93938 through 93939)

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IM injections may be administered independently or alongside IV therapy depending on your treatment goals and care recommendations