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72 TP53BP2 IS ASSOCIATED WITH HBsAg CLEARANCE IN PEGINTERFERON-ALFA-TREATED CHRONIC HEPATITIS B Guiwen Guan 1 , Xiangmei Chen 1 and Fengmin Lu 1,2 , (1)Peking University, (2)Peking University Peoples Hospital Background: Hepatitis B surface Antigen (HBsAg) loss occurs in a minor fraction of patients with Chronic Hepatitis B (CHB) under interferon therapy

For example, studies have identified genes such as brain-derived neurotrophic factor (BDNF) and the serotonin transporter gene (SLC6A4) as being closely associated with depression susceptibility [292,293,294]