l-carnitine and l-theanine together The carnitine system cancer metabolic plasticity NOW Foods Acetyl L-Carnitine 500

Mol Pharmacol 21:629631 Conigrave AD, Hampson DR (2006) Broad-spectrum L-amino acid sensing by class 3 G-protein-coupled receptors

This localized neuroinflammation and metabolic starvation in the brain are primary drivers of the severe cognitive impairment, or "brain fog," that plagues so many long-haulers

R Met/Met individuals have higher synaptic dopamine and norepinephrine (because COMT clears them more slowly), which improves prefrontal cortex function and working memory but increases susceptibility to stress-related anxiety, pain sensitivity, and catechol estrogen accumulation

Interestingly, it has been reported that OGT and Ezh2 co-repress a defined tumor suppressor genes in breast and colon cancer cells