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For GSTM1 and GSTT1 status with only two possible genotypes, the odds ratio was compared between cases and controls by the Mantel-Haenszel method

In contrast, GSH treatment did not significantly improve the GSH/GSSG ratio at any of the tested doses, indicating that exogenous GSH alone may be insufficient to restore redox balance under the given experimental conditions

Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis

On the basis of experimental in vitro studies, it has been strongly suggested that the inhibitory effect of iodine excess on NIS expression involves the generation of ROS