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Description

Epidemiology of liver cirrhosis Liver cirrhosis is the result of fibrosis and necrotizing inflammation stemming from various mechanisms of liver injury (Figure 1)

Subhan et al., 2018)

Thus, the excess PyroGlu in a septic patient without an enzymatic deficit in the gamma-glutamyl cycle could be associated with GSH depletion, and therefore excessive oxidative stress and its negative consequences