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Figure 6 To assess how cellular communication in the DRG is altered under different conditions, we also analyzed differentially expressed ligand and receptor genes using bulk RNA sequencing (RNA-seq) data from both normal and sciatic nerve injury (SNI) conditions

In vivo study found that intraperitoneal injection of 100 mg/kg silibinin in a surgical EMs mouse model, combined with in vitro treatment of VK2/E6E7 and End1/E6E7 cells with 050 M silibinin, demonstrated that silibinin dose-dependently inhibited cell proliferation, suppressed DNA replication, induced ROS production by modulating the MAPK signaling pathway, thereby promoting apoptosis ( Naringenin is a naturally occurring dihydroflavonoid compound

After staining, the sections were dehydrated with xylene, and mounted using Mount-Quick (Daido Sangyo, Saitama, Japan)

Side effects of beta-2-agonists include increased heart rate and blood pressure, trembling, and cardiac arrhythmias (Littner 2011)