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Obesity is associated with several health complications, including an increased risk of co-morbidities, including type 2 diabetes, cardiovascular disease, chronic kidney disease (CKD) and metabolic dysfunction-associated steatohepatitis (MASH)

References National Center for Biotechnology Information (NCBI) Human Chorionic Gonadotropin: structure, function, and LH receptor binding mechanisms Seminars in Reproductive Medicine Pharmacokinetics and pharmacodynamics of HCG: extended halflife and sustained activity Translational Andrology and Urology (2018) Lee JA & Ramasamy R: Review of hCG for hypogonadal male infertility (typical regimens: 1,5005,000 IU 23/week) The Journal of Clinical Endocrinology & Metabolism (2005) Coviello AD et al: Lowdose hCG maintains intratesticular testosterone in men with testosteroneinduced gonadotropin suppression Male Infertility Guide Clinical commentary on hCG dosing: 500 IU SC 3/week for maintenance

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13 C-labeled B12 absorption test 13 Ccyanocobalamin is a safe stable isotope-labeled vitamin B12 also biosynthesized from Salmonella enterica (Devi et al., 2020)