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Based on several clinical trials, applying consolidative allo-HSCT following the CD19 CAR-T cell therapy R/R B-ALL patients indicated the encouraging outcomes with an acceptable level of safety and efficacy

Elevated lactate implies potential mitochondrial dysfunction, with an increased reliance on glycolysis for ATP production (Mathew et al., 2009

The reduction in GSSG levels might represent a distinct pathophysiological state in acute relapse, possibly involving different mechanisms from those in first-episode or stable phases of the illness [32]

Aimee: Basically, the message is its not too late if you start making those changes even three weeks before