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Gene expression analysis compares the differential expression of genes between patients with depression and healthy controls, enabling the identification of key genes associated with depression

Common MDs (distinguished as childhood- or adult-onset MDs) include clinical syndromes such as Leigh syndrome, AlpersHuttenlocher syndrome (AHS), Leber hereditary optic neuropathy (LHON) and KearnsSayre syndrome (KSS) [8]

1 H NMR (400 MHz, DMSO- d 6 ) 12.30 (s, 1H), 10.99 (s, 1H), 7.69 (dt, J = 11.0, 5.5 Hz, 1H), 7.587.48 (m, 2H), 7.40 (d, J = 7.0 Hz, 1H), 6.766.65 (m, 1H), 5.13 (dd, J = 13.3, 5.1 Hz, 1H), 4.30 (dd, J = 58.2, 17.4 Hz, 3H), 4.06 (s, 2H), 3.87 (d, J = 11.7 Hz, 1H), 3.153.09 (m, 2H), 3.01 (t, J = 12.3 Hz, 1H), 2.952.86 (m, 1H), 2.752.54 (m, 4H), 2.492.37 (m, 2H), 2.051.98 (m, 1H), 1.82 (dd, J = 14.1, 7.2 Hz, 4H), 1.53 (d, J = 12.5 Hz, 1H), 1.40 (d, J = 9.4 Hz, 1H), 1.18 (d, J = 3.6 Hz, 9H)