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In DPN, particularly omega-3s, demonstrate protective mechanisms through the anti-inflammatory effect, antioxidant pathways (mostly Nrf2 pathway), membrane stability and improved conduction velocity [113]

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3.1C Plaque Area Two Condition: For the baseline duplex Doppler ultrasonography, the total number of pieces counted in plaque area Number Two were 42 with the follow up study showing a total of 40