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[01:12:38] Chad: I did too

Recently Ma et al., using multiparametric analysis of GPX4 and Apoptosis Inducing Factor Mitochondria Associated 2 (AIFM2) also called ferroptosis suppressor protein (FSP1) expression and function identified high expression of both proteins as novel biomarkers of pejorative prognosis in AML [35]

Because topology of RGC loss and defects in the visual field (radial in humans, sectorial in rodents) correlate with the position of axons within the ONH (10, 38), the ONH is widely seen to be important in determining the extent of final axonal damage that drives neurodegeneration

These changes not only affect cardiovascular health but may also exacerbate depressive symptoms and neurodegenerative processes (130) ( Figure 2E )