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It has been reported that familial PBC is related to maternally inherited factors, and that the disease tends to present earlier in the second generation [52], and is most common in mother-daughter and sister-sister combinations [53]

Extended room temperature exposure (over 24 hours) accelerates degradation noticeably

Five-Year New Chemical Entity (NCE) Exclusivity Granted to drugs containing an active moiety never before approved by the FDA under any NDA

Enzyme-responsive cell-penetrating peptide conjugated mesoporous silica quantum dot nanocarriers for controlled release of nucleus-targeted drug molecules and real-time intracellular fluorescence imaging of tumor cells