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In another study, miR-1611 was demonstrated to be upregulated in leg muscles that are rich in slow-twitch fibers and could target the SIX homeobox 1 ( Six1 ) gene, facilitating the transition from fast- to slow-twitch fibers

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In the pathogenesis of type 2 diabetes, aberrant immune cell activation and the accompanying chronic inflammatory milieu are consequences of diabetes, which in turn lead to pathologic damage and disease progression

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