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The stress factor GDF15 is frequently upregulated in cachexia, in both patients and preclinical models, and is implicated in anorexia, adipose and muscle wasting, making it a promising therapeutic target for cachexia syndrome (Sohail Ahmed et al., 2021)

Zabocka-Sowiska K, Paczkowska S, Skrska K, Prescha A, Paweczyk K, Porbska I, Kosacka M, Grajeta H (2019) Oxidative stress in lung cancer patients is associated with altered serum markers of lipid metabolism