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Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase

Tables I (writers) and II (erasers) (3,7,2062) collectively provide an enzymatic perspective on the functional consequences of Kla, offering a comprehensive summary of specific lactylation sites and their associated biological functions

Upon antigenic stimulation, adaptive immunity in diabetic patients produces lower levels of immune responses, including reduced cell activation and proliferation as well as reduced cytokines (145, 146)

However, the specific substrate targeted by RNF135 was not investigated in that study