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Of all included studies, 25 were conducted in mice and 27 in rats (Fig

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The first group was set as control group without any treatment, while mice in the following four groups were injected with complete Freunds adjuvant (20 L) in their right hind ankle joints, for establishing an AIA model

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Studies identified as not relevant during the screening process did not move forward to data extraction or study quality evaluation

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doi: 10.1186/s12906-018-2409-0

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