glutathione s-transferase pi gstp function Frontiers The role of glutathione S-transferases

Free Radic Biol Med 2016;97:489-500

First isolated from human plasma by Loren Pickart in 1973 during research on components that could stimulate liver regeneration, GHK was initially recognized for its ability to promote tissue repair and remodeling

By reframing iron pathology as a problem of iron stasis rather than simple overload, we challenge conventional interpretations of iron in neurodegeneration and highlight the need to consider both iron immobilisation and metabolic insufficiency as central determinants of ferroptosis-related disease mechanisms

doi:10.2174/0929867325666180313105949 [PubMed] [BenthamScience] Zhang H, Tsao R