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Early response to antipsychotic therapy as a clinical marker of subsequent response in the treatment of patients with first-episode psychosis

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The initiation and progression of AD is characterized by disturbances in intracellular proteostasis due to the alteration of protein synthesis, folding, surveillance, and degradation, which trigger the accumulation of altered proteins and toxic aggregates, widely recognized to be implicated in this phenomenon (327, 330332)

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