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Moreover, In non-cancer contexts, CBD has been shown to protect nucleus pulposus cells from HO-induced damage by reducing iNOS, COX-2, and pro-inflammatory cytokines (IL-1, IL-6) while enhancing anti-apoptotic Bcl-2 (Aviello et al

It should be noted that the absolute values should be considered in relation to the cellular concentration of the GST, such that the approximately 3- to 4-fold lower specific activities of SscGST A2-2, CjaGST A3-3, and HsaGST A1-1, if required, could be compensated for by a higher expression level of the protein

(PubMed) Charoensiriwatana W, Srijantr P, Teeyapant P, Wongvilairattana J