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(2022, January 28)

Challenges and Limitations in Implementation Barriers to Clinical Change Provider resistance to changing established diagnostic approaches represents a major implementation barrier

Costantini TW, Krzyzaniak M, Cheadle GA et al (2012) Targeting -7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury

Other proposed contributors discussed in the literature include modulation of the dopaminergic and serotonergic systems, growth hormone receptor expression in fibroblasts, and interaction with the nitric oxide system at the level of vasomotor regulation (Sikiric et al., 2018)