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3 Mood and anxiety disorders 3.1 Major depressive disorder (MDD) The microbiota of patients suffering from MDD represents much less diversity and altered abundances of taxonomies involved in neurotransmitter synthesis and immune modulation, both mainly consistent in terms of pointing toward dysbiosis (Barandouzi et al., 2020

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This specificity is central to the ability of IECs to distinguish between harmless structures associated with microbiota residents and those of enteric pathogens, thereby limiting the occurrence of exaggerated IRs in the gut (Allaire et al