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Description

Inhibition of nf-kappab and wnt/beta-catenin/gsk3beta signaling pathways ameliorates cardiomyocyte hypertrophy and fibrosis in streptozotocin (Stz)-induced type 1 diabetic rats

Figure 2 Interactions between NO and antioxidants The versatility of signaling by RNS and ROS is further extended by their interaction with antioxidants

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Theoretically, chronic lipolysis activation could deplete essential lipid stores or disrupt adipose tissue-derived signaling pathways (via adipokines), though this remains speculative