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IGF-1 LR3 Synonyms / Designations: IGF-1 LR3, Long Arg IGF-1, Insulin-Like Growth Factor-1 LR3, Recombinant IGF-1 analogue CAS Number: 946870-92-4 Molecular Formula: C400H625N111O115S9 Molecular Weight: 9117.5 g/mol Peptide Classification: Synthetic analogue of insulin-like growth factor-1 (IGF-1) Purity: 99 % (HPLC, typical) Appearance: White to off-white lyophilised powder Pack Size: 1 mg (total) Storage: Desiccated, protected from light, stored at 20 C Solubility: Soluble in sterile water and buffered aqueous solutions Description & Mechanism IGF-1 LR3 is a synthetic analogue of human insulin-like growth factor-1 (IGF-1) incorporating an arginine substitution at position 3 and an extended N-terminal sequence

This point is highly relevant, as one of the central roles of A is the modulation of synaptic plasticity (Parihar and Brewer, 2010), a process itself that is regulated by copper efflux into the synapse that can influence the excitability of NDMA, AMPA, and GABA receptors as well as vesicular trafficking (DAmbrosi and Rossi, 2015)

It was identified, isolated, and characterized by a research group at the University of Zagreb led by Predrag Sikiric, who has been the central figure in the BPC-157 literature for more than two decades