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Plasma levels drop from approximately 200ng/ml at age 20 to 80ng/ml by age 60

Several topics require future in-depth investigations, such as the clinical benefit of using prophylactic B12 supplementation in some groups who are at risk of B12 deficiency due to accompanying diseases or medications

Typically, patients begin Zepbound treatment with a low dose to minimize side effects, especially gastrointestinal symptoms such as nausea, diarrhea, constipation or abdominal discomfort