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Description

Complete Blood Count (CBC): To check for macrocytic anemia (abnormally large red blood cells), a hallmark of severe B12 deficiency

Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells

The therapeutic alliance between clinicians and patients has also emerged as a key factor, as participants often report that the relationship with the therapist strengthens their motivation to adhere to lifestyle changes