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The stable binding of the pyran glucoside part of Arbutin_d around the metal site also suggests that -Arbutin may have multiple binding tendencies with hTYR

These studies have revealed that adolescent THC exposure induces core schizophrenia-related endophenotypes resembling positive and negative symptoms, such asocial motivation deficits, affective dysregulation, cognitive and sensorimotor gating abnormalities [4, 5]

Some studies have reported increased markers of lipid and DNA oxidation, particularly in poorly controlled diabetic dogs, suggesting an association with disease severity [111,113]

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