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Metabolism of aromatic amino acids, particularly tryptophan, is another example for the tight interplay of microbiome and host metabolism 124

For instance, Lactobacillus rhamnosus can regulate the abundance of beneficial bacteria in the gut microbiota of zebrafish larvae, thereby affecting the transcription of genes related to cholesterol-triglyceride metabolism and modulating host lipid processing and metabolism [55]

Furthermore, alcohol induces StARD1 expression in perivenous hepatocytes and increases mitochondrial cholesterol accumulation and loss of mitochondrial ultrastructure architecture [204]