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Consistent with this, studies in mice further showed that paclitaxel-induced mechanical hypersensitivity is mediated by keratinocytes, whereas optogenetic or chemogenetic keratinocyte inhibition largely alleviated the symptoms during acute and long-term exposure (93)

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Makkar SR, Zhang SQ, Cranney J (2010) Behavioral and neural analysis of GABA in the acquisition, consolidation, reconsolidation, and extinction of fear memory