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2-ketobutyrate derived from threonine catabolism inhibits mitochondrial pyruvate dehydrogenase, impairing acetyl-CoA generation and promoting lipid peroxidation via ROS overproduction (61)

The magnetic resonance imaging (MRI) revealed a large cystic and solid lesion in the pelvic and abdominal cavity, internally segmented by multiple septa, with approximate dimensions of 11.7cm x 8.7cm x 19.1cm ( Figure 1B )

Bile helps give stool its brown color, so pale stool may be connected with liver, gallbladder, bile duct, or pancreas issues

Frozen single-use aliquots at minus 20C can extend usability to around 90 to 120 days, though potency still drops slightly each week