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[15] Keep vials in their original packaging

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For the design of synthetic ligands, information about structure of the target protein and a potential binding site are required, thus a structure-based design can be achieved, in case correct prediction of the ligands comformation and the binding affinity of the designed ligand

Specifically, under Gln+ conditions, highly active c-Myc represses miR-29b-3p transcription, leading to a substantial reduction in its expression