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In another glutamatergic-targeted study, NitroSynapsin administration in Mef2c +/ mice increased the number of NeuN-positive cells and the levels of VGAT and parvalbumin-positive synapses, without altering the number of parvalbumin-positive neurons within the hippocampus

As it stands, Epitalons pharmacological profile is promising but incomplete, raising key questions about long-term safety, optimal dosing, and how to harness its effects in a reliable, standardized way

Microbiome-targeted interventions like probiotics and diet have shown potential to modulate immune activity and may reduce disease activity, though more robust clinical evidence is needed

Next, we compared the functional performance of differentiated h-HepOrgs to that of PHHs