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Lipoic acid has also been shown in preclinical research to improve nerve blood flow and conduction velocity and to confer mitochondrial protective effects (Viana 2022

doi:10.1113/jphysiol.2010.201343

The role of gut microbiota metabolite trimethylamine N-oxide in functional impairment of bone marrow mesenchymal stem cells in osteoporosis disease

Various plant derivatives, such as alkaloids, flavonoids, and terpenoids, have been extensively addressed for their anti-proliferative effects on multiple cancer types [113]