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306 Exposure to arsenic can result in toxicity, primarily caused by the generation of reactive oxygen intermediates during its redox cycling and metabolic activation

Arsenic methylation capacity and skin cancer

Moreover, studies indicate that PDAC cells, through TGF-1 and lysophosphatidic acid (LPA) signaling, induce mPSCs to adopt a more myCAF-like phenotype, which then secretes type I collagen to suppress tumor dissemination [41, 68, 69]