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MeCbl is promisingly to be repurposed as an effective therapeutic drug against liver failure executed by GSDME dependent pyroptosis, which may be dominant in cholestatic, chemotherapeutics, and autoimmune hepatitis triggered liver failure

doi: 10.1172/jci.insight.132747 106 MaXMeiSWuyunQZhouLSunDYanJ

A., Wang, H., Maller, G., DeSouza, R., & Khan, I

By altering CD44 distribution in FRCs, vCD44BP might impair dendritic cell migration and the resulting dendritic cellT cell interactions required for optimal T cell priming