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Table 6: Treatment of folate deficiency (adapted from Means 2021) 27 TOP Ongoing Care Ongoing Management Vitamin B 12 Duration of therapy Once a diagnosis of B 12 deficiency due to poor absorption of B 12 has been made, therapy should be maintained lifelong

This can lead to numbness and tingling in your hands and feet, mental confusion, weight loss, and generally feeling wiped out and weak, as reported by the Mayo Clinic

Preliminary data from trials involving daratumumab with Pembrolizumab (a PD-1 inhibitor), Atezolizumab (another PD-1 inhibitor), and TTI-622 (a CD47 inhibitor) suggest potential synergistic effects, offering new avenues for MM treatment [77]

We sought comment on how CMS could identify service pairings or clusters of services for complexity adjustments that are clinically appropriate but are currently not evaluated for complexity adjustments