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Rating: 4.869400000000001 (18 reviews)

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Description

Spectrin deficiency has been identified in asymptomatic Dutch Golden Retrievers , which displayed increased osmotic fragility, but no spherocytes were evident in blood smears (Slappendal et al 2005)

Chk2, a serine/threonine kinase, is activated in response to DNA damage, and it plays an essential role in controlling DNA repair, cell cycle arrest, and apoptosis

10.1242/jcs.161216 155 WongY

As an advantage, BiTE can link T cells and tumor cells without restriction to MHC and induce T cells' activation, proliferation, and cytotoxic function efficiently [105]