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Consider a pre-emptive decrease in warfarin of up to 30% when this antibiotic is added to warfarin, and expect the interaction to kick in relatively quickly - just a couple of days

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Non-ionic surfactants (which do not undergo ionization when being dissolved in water): Polyethylene glycol (PEGs) Anionic surfactants: sodium lauryl sulfate, ammonium lauryl sulfate Cationic surfactants: quaternary ammonia compounds with positively charged surface-active moieties (benzalkonium, benzethonium, cetylpyridinium, methylbenzethonium) As per USP General Chapter 1092 Physical and chemical characteristics of the drug substance need to be determined as part of the process of selecting the proper dissolution medium