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10.1038/s41556-022-00949-1 13 ClaraA.MartaK.PaulaM.-S.Lpez-PoloV.TorresT.PuigS.et al (2024)

Medicine has a long history of compounds that looked extraordinary in rodents, but failed or caused harm in people

They target completely different receptor systems in the brain to reduce appetite through separate neural pathways

The compound's therapeutic potential stems from its ability to modulate multiple cellular pathways, including extracellular matrix synthesis, metalloproteinase regulation, and inflammatory mediator control