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In addition, long-lived radionuclides are required to match the biological half-life of mAb-based tracers due to their interaction with the neonatal Fc receptor (FcRn) in endothelial cells, which protects serum IgG from degradation [106]

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Common Side Effects While uncommon, some people may experience mild side effects after receiving a B12 injection, including[17]: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling or numbness in the hands and feet These effects are typically short-lived and resolve on their own