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It was presumed that this was an additional adulterant in patients who presented with opioid withdrawal because local data in Philadelphia, where the study took place, showed 98% of all non-medical opioid samples tested contained both fentanyl and xylazine

In summary, oxidative stress plays a pivotal role in male infertility, primarily through its deleterious effects on spermatozoa, which manifest as diminished motility, reduced fertilization capabilities, and compromised genetic integrity