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10.1186/s12974-020-01842-0 21 GongZ.TassetI.DiazA.AnguianoJ.TasE.CuiL.et al (2018)

Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK)

The activated iodine binds to tyrosine residues on thyroglobulin molecules under the action of TPO to produce monoiodotyrosine (MIT) and diiodotyrosine (DIT), which are subsequently coupled to produce T3 or T4 ( Figure 1 )