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[1] A few days later, the skin begins to blister and peel, forming painful raw areas

Case reports document life-threatening potassium elevations and fatal arrhythmias when arginine infusions were administered to individuals with diminished renal or hepatic clearance, illustrating that even short-duration dosing can overwhelm compromised excretory pathways

One possibility is that, after endosome acidification, folate is dissociated from FR and is transported into cytosol through PCFT

It may occur when the individual is engaged in other activities such as watching television, reading, studying and talking on the phone