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6a), and the FBP-mediated conformational changes in RCC2 localized to a loop facing the presumed interface for Rac1 interaction (Fig

Rather than allowing peptide use to remain confined to nonmedical distribution channels, orthopedics should lead the development of standardized perioperative registries and prospective trials using verified formulations, with the goal of determining whether peptide-based therapies can be safely integrated into evidence-based surgical optimization

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