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(54) PATHOPHYSIOLOGY OF ALCOHOL AND CIRRHOSIS Acetaldehyde is a metabolite of alcohol that, when it accumulates, produces liver damage as the result of its ability to generate formation of DNA adducts such as sites without purine or pyrimidine (Figure 3)

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The negative correlation of serum iron content with muscle mass provides new perspectives on preventing and treating muscle loss

GSH augmentation deserves investigation as a beneficial therapeutic approach for not only PD but also numerous other CNS disorders for which GSH deficiency and GSH-related enzyme deficits have been documented (multiple sclerosis, 25,26 autism, 2729 Alzheimers disease, 30,31 schizophrenia, 32,33 and bipolar disease 34 )