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In AD, an imbalance between Th1 and Th2 cells is recognized as one of the most prominent immunological hallmarks

Sankowski AJ, Lebkowska UM, Cwikla J, Walecka I, Walecki J

The cell migration gene family DLX (such as DLX1, DLX2, DLX5/6) are homeodomain transcription factors that primarily govern the generation and migration of GABAergic interneurons in the forebrain

The pathogenesis of POI is complex and multifactorial and may be caused by defects in primordial follicle formation, follicle recruitment/distribution, follicle growth and development [46, 47]