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For TME-oriented nanoplatforms to move beyond conceptual appeal, they need to be assessed in relation to route of administration, clinical evidence, directness of TME effect, biomarker use, CMC feasibility, safety and value [21, 62, 105]

Numerous studies have indicated that SASP does not exert solely positive effects [31, 34, 37, 38]

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(2018) Surgical management of the recurrent laryngeal nerve in thyroidectomy: American Head and Neck Society Consensus Statement