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Also, a similar protocol was successful in the therapy of the other fistulas, that is, gastrocutaneous (Skorjanec et al., 2009), esophagocutaneous (Skorjanec et al., 2015), vesicovaginal (Seiwerth et al., 1997

As a result, V-B12 can encounter NO released by endothelial cells before Hb does, with the overall efficacy dictated by the relative concentrations of V-B12 and NO near the endothelial cells

While this property remains partially characterized, it explains reported benefits for conditions involving brain and spinal cord tissue

The need for, and frequency of dosing is related to the severity of deficiency and age of the animal