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Agents that upregulate Bcl-2 or mimic its protective function, such as Bcl-2 overexpression vectors and BH3 mimetics, help preserve mitochondrial integrity (62)

2023;62(22):e202301074

The core mechanism of action of IGF-1 LR3 IGF-1 LR3 activates downstream signaling pathways (such as the AKT/mTOR pathway) by binding to the IGF-1 receptor (IGF1R) on the cell surface, regulating cell proliferation, differentiation, migration, and metabolism