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People with pernicious anaemia will typically have other autoimmune conditions, such as type 1 diabetes mellitus, Hashimotos thyroiditis, Graves disease and vitiligo[7]

doi:10.1124/jpet.111.182220

Some of the more serious reactions from the central nervous system that were observed with tricyclic antidepressants were noted in short-term studies using cyclobenzaprine for other indications, except for muscle spasm associated with acute disorders of the musculoskeletal system, and mainly in doses, of several higher than those recommended for eliminating skeletal muscle spasm