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In an early phase (within 1 h after administration), NR and NAM were directly taken up by the small intestine and utilized for NAD + synthesis in the liver [29]

monitoring is reasonable in chronic use

Striegel H, et al

This review synthesizes these multifaceted resistance pathways and parallels them with the challenges in vaccine development, highlighting the limited efficacy of Bacillus Calmette-Gurin and the promise of next-generation candidates